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ML-297

Product Specifications

CAS Number

1443246-62-5

Synonyms

VU 0456810, CID 56642816

Target

Potassium Channel

Applications

Transmembrane Transporters

Smiles

CC1=NN (C (=C1) NC (=O) NC2=CC (=C (C=C2) F) F) C3=CC=CC=C3

Molecular Formula

C17H14F2N4O

Additionnal Information

ML-297 (VU 0456810, CID 56642816) is a potent and selective activator of Kir3.1/3.2 (G protein-coupled inwardly rectifying potassium, GIRK1/2) channel with EC50 of 0.16 μM and 1.8 μM for GIRK1/2 and GIRK1/4, respectively. ML-297 is potential for the treatment of epilepsy.

Storage Conditions

3 years -20°C powder

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