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B-Raf IN 1

Product Specifications

CAS Number

950736-05-7

Target

Raf

Applications

MAPK

Smiles

CN (C) CC1=CC=C (C=C1) C2=C3N=CC=C (N3N=C2) C4=CC (=CC=C4) NC (=O) C5=CC (=CC=C5) C (F) (F) F

Molecular Formula

C29H24F3N5O

Additionnal Information

B-Raf IN 1 is an inhibitor of Raf wih IC50 values of 24 nM and 25 nM for B-Raf and C-Raf respectively. It is selective over 13 other kinases, including PKCα, IKKβ, and PI3Kα.

Storage Conditions

3 years -20°C powder

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