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AG 555

Product Specifications

CAS Number

133550-34-2

Synonyms

Tyrphostin B46

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

C1=CC=C (C=C1) CCCNC (=O) C (=CC2=CC (=C (C=C2) O) O) C#N

Molecular Formula

C19H18N2O3

Additionnal Information

AG-555 (Tyrphostin B46) is an inhibitor of tyrosine kinase, interacts directly with topoisomerase I, thus preventing DNA relaxation. It inhibits EGFR with an IC50 of 0.7 μM.

Storage Conditions

3 years -20°C powder

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