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GNE-477

Product Specifications

CAS Number

1032754-81-6

Target

PI3K

Applications

PI3K/Akt/mTOR

Smiles

CC1=C (SC2=C1N=C (N=C2N3CCOCC3) C4=CN=C (N=C4) N) CN5CCN (CC5) S (=O) (=O) C

Molecular Formula

C21H28N8O3S2

Additionnal Information

GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with an IC50 of 4 nM for PI3Kα and Kiapp of 21 nM for mTOR.

Storage Conditions

3 years -20°C powder

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