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Y-27632

Product Specifications

CAS Number

146986-50-7

Target

ROCK

Applications

Cytoskeletal Signaling

Smiles

CC (N) C1CCC (CC1) C (=O) NC2=CC=NC=C2

Molecular Formula

C14H21N3O

Additionnal Information

Y-27632 is a selective ROCK1 and ROCK2 inhibitor with a Ki of 140 nM and 300nM in a cell-free assay, exhibits >200-fold selectivity over other kinases, including PKC, cAMP-dependent protein kinase, MLCK and PAK.

Storage Conditions

3 years -20°C powder; 2 years -80°C in solvent

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