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1-NM-PP1

Product Specifications

CAS Number

221244-14-0

Synonyms

PP1 Analog II, 1NM-PP1

Target

Src

Applications

Protein Tyrosine Kinase

Smiles

CC (C) (C) [N]1N=C (CC2=CC=CC3=CC=CC=C23) C4=C (N) N=CN=C14

Molecular Formula

C20H21N5

Additionnal Information

1-NM-PP1 (PP1 Analog II, 1NM-PP1, analogue 9) is a potent inhibitor of Src family kinases with IC50 of 4.3 nM and 3.2 nM for v-Src-as1 and c-Fyn-as1, respectively. 1-NM-PP1 also inhibits CDK2-as1, CAMKII-as1 and c-Abl-as2 with IC50 of 5.0 nM, 8.0 nM and 120 nM, respectively.

Storage Conditions

3 years -20°C powder

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