5'-N-Ethylcarboxamidoadenosine (NECA)
Product Specifications
CAS Number
35920-39-9
Synonyms
5'- (N-Ethylcarboxamido) adenosine, Adenosine-5'N-ethylcarboxamide, 5'-Ethylcarboxamidoadenosine
Target
Adenosine Receptor
Applications
GPCR & G Protein
Smiles
CCNC (=O) C1OC (C (O) C1O) [N]2C=NC3=C (N) N=CN=C23
Molecular Formula
C12H16N6O4
Additionnal Information
5'-N-Ethylcarboxamidoadenosine (NECA, 5'- (N-Ethylcarboxamido) adenosine, Adenosine-5'N-ethylcarboxamide, 5'-Ethylcarboxamidoadenosine) is a stable, nonselective adenosine receptor agonist. 5'-N-Ethylcarboxamidoadenosine acts via multiple mechanisms including: reducing diabetes-induced oxidative stress, inhibiting gene expression of IL-18, TNF-α and ICAM-1 (intercellular adhesion molecule 1 (CD54) ), and blocking activation of the JNK-MAPK pathway.
Storage Conditions
3 years -20°C powder
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