Indophagolin
Product Specifications
CAS Number
1207660-00-1
Target
P2 Receptor
Applications
Neuronal Signaling
Smiles
FC (F) (F) C1=C (Cl) C=CC (=C1) N[S; v6] (=O) (=O) C2=C (Br) C=C3CCN (C (=O) C4CC4) C3=C2
Molecular Formula
C19H15BrClF3N2O3S
Additionnal Information
Indophagolin, a potent indoline-containing autophagy inhibitor with IC50 of 140 nM, antagonizes the purinergic receptor P2X4 as well as P2X1 and P2X3 with IC50s of 2.71, 2.40 and 3.49 μM, respectively, also has a strong antagonistic effect on serotonin receptor 5-HT6 with IC50 of 1.0 μM.
Storage Conditions
3 years -20°C powder
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