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HPK1-IN-2

Product Specifications

CAS Number

2056122-11-1

Target

Serine/threonin kinase

Applications

Cell Cycle

Smiles

CN1CCN (CC1) C2=CC=C3N=C ([NH]C3=C2) C4=C (N) C5=C (NC4=O) SC=C5

Molecular Formula

C19H20N6OS

Additionnal Information

HPK1-IN-2 is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1, a serine/threonine Ste20-related protein kinase), Lck and Flt3 with IC50 of <0.05 μM, IC50 of <0.5 μM and IC50 of <0.05 μM, respectively. HPK1-IN-2 exhibits antitumor activity.

Storage Conditions

3 years -20°C powder

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