HPK1-IN-2
Product Specifications
CAS Number
2056122-11-1
Target
Serine/threonin kinase
Applications
Cell Cycle
Smiles
CN1CCN (CC1) C2=CC=C3N=C ([NH]C3=C2) C4=C (N) C5=C (NC4=O) SC=C5
Molecular Formula
C19H20N6OS
Additionnal Information
HPK1-IN-2 is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1, a serine/threonine Ste20-related protein kinase), Lck and Flt3 with IC50 of <0.05 μM, IC50 of <0.5 μM and IC50 of <0.05 μM, respectively. HPK1-IN-2 exhibits antitumor activity.
Storage Conditions
3 years -20°C powder
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