Losartan Carboxylic Acid (EXP-3174)
Product Specifications
CAS Number
124750-92-1
Synonyms
E-3174
Target
Angiotensin Receptor
Applications
GPCR & G Protein
Smiles
CCCCC1=NC (=C ([N]1CC2=CC=C (C=C2) C3=CC=CC=C3C4=N[NH]N=N4) C (O) =O) Cl
Molecular Formula
C22H21ClN6O2
Additionnal Information
Losartan Carboxylic Acid (E-3174, EXP-3174), an active carboxylic acid metabolite of Losartan, is a non-peptide angiotensin II (AT1) receptor antagonist. Losartan Carboxylic Acid inhibits the specific binding of [125I]-angiotensin II to VSMC with IC50 of 1.1 nM.
Storage Conditions
3 years -20°C powder
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