Metformin
Product Specifications
CAS Number
657-24-9
Synonyms
1,1-Dimethylbiguanide
Target
AMPK
Applications
PI3K/Akt/mTOR
Smiles
CN (C) C (=N) NC (N) =N
Molecular Formula
C4H11N5
Additionnal Information
Metformin (1,1-Dimethylbiguanide), a widely used drug for treatment of type 2 diabetes, activates AMP-activated protein kinase (AMPK) in hepatocytes. Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153.
Storage Conditions
3 years -20°C powder
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