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Metformin

Product Specifications

CAS Number

657-24-9

Synonyms

1,1-Dimethylbiguanide

Target

AMPK

Applications

PI3K/Akt/mTOR

Smiles

CN (C) C (=N) NC (N) =N

Molecular Formula

C4H11N5

Additionnal Information

Metformin (1,1-Dimethylbiguanide), a widely used drug for treatment of type 2 diabetes, activates AMP-activated protein kinase (AMPK) in hepatocytes. Metformin promotes mitophagy in mononuclear cells. Metformin induces apoptosis of lung cancer cells through activating JNK/p38 MAPK pathway and GADD153.

Storage Conditions

3 years -20°C powder

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