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Solcitinib

Product Specifications

CAS Number

1206163-45-2

Synonyms

GLPG0778, GSK2586184

Target

JAK

Applications

Angiogenesis

Smiles

CC1 (CN (C1) C (=O) C2=CC=C (C=C2) C3=CC=CC4=NC (=NN43) NC (=O) C5CC5) C

Molecular Formula

C22H23N5O2

Additionnal Information

Solcitinib (GLPG0778, GSK2586184) is an inhibitor of JAK1 with an IC50 of 8-9 nM, and shows 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively.

Storage Conditions

3 years -20°C powder

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