Poloxin
Product Specifications
CAS Number
321688-88-4
Target
PLK
Applications
Cell Cycle
Smiles
CC (C) C1=CC (=N/OC (=O) C2=CC=CC=C2C) /C (=CC1=O) C
Molecular Formula
C18H19NO3
Additionnal Information
Poloxin is a non-ATP competitive Polo-like Kinase 1 polo-box domain (Plk1 PBD) inhibitor with an apparent IC50 of 4.8 μM. Poloxin's IC50 values against the PBDs of Plk2 and Plk3 as Plk1 are approximately 4-fold and 11-fold higher, respectively in fluorescence polarization assays.
Storage Conditions
3 years -20°C powder
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