CY-09

Product Specifications

CAS Number

1073612-91-5

Target

NLRP3

Applications

Immunology & Inflammation

Smiles

C1=CC (=CC (=C1) C (F) (F) F) CN2C (=O) C (=CC3=CC=C (C=C3) C (=O) O) SC2=S

Molecular Formula

C19H12F3NO3S2

Additionnal Information

CY-09 is a specific NLRP3 inflammasome inhibitor that directly targeted NLRP3 itself. It is tested against the five major cytochrome P450 enzymes 1A2, 2C9, 2C19, 2D6, and 3A4 with half maximal inhibitory concentration (IC50) values of 18.9, 8.18, >50, >50, and 26.0 μM, respectively.