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Bedaquiline

Product Specifications

CAS Number

843663-66-1

Synonyms

TMC-207, R207910

Target

ATPase

Applications

Transmembrane Transporters

Smiles

CN (C) CCC (C1=CC=CC2=CC=CC=C21) (C (C3=CC=CC=C3) C4=C (N=C5C=CC (=CC5=C4) Br) OC) O

Molecular Formula

C32H31BrN2O2

Additionnal Information

Bedaquiline (TMC-207, R207910), a diarylquinoline, binds to subunit c of mycobacterial ATP synthase and inhibits its activity. It is highly selective for mycobacterial ATP synthase enzyme compared to homologous eukaryotic enzyme (Selectivity Index >20 000) .

Storage Conditions

3 years -20°C powder

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