CYP51-IN-17
CYP51-IN-17 (compound 7a) is a potent CYP51 inhibitor with an IC50 of 0.377 μg/mL. CYP51-IN-17 shows significant fungicidal activity against B. cinerea with an EC50 of 0.326 μg/mL[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial; Cytochrome P450; Fungal
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cyp51-in-17.html
Smiles
O=C(C(C1C2=CC=CO2)=C(N)OC3=C1CN(C(C4=CC=CO4)=O)C/C3=C\C5=CC=CO5)OC
Molecular Formula
C24H20N2O7
Molecular Weight
448.42
References & Citations
[1]Bao A, et al. Design, Synthesis, Bioactive Evaluation, and Molecular Dynamics Simulation of Novel 4 H-Pyrano [3, 2-c] pyridine Analogues as Potential Sterol 14α-Demethylase (CYP51) Inhibitors[J]. Journal of Medicinal Chemistry, 202
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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