CYP51-IN-17
Product Specifications
UNSPSC Description
CYP51-IN-17 (compound 7a) is a potent CYP51 inhibitor with an IC50 of 0.377 μg/mL. CYP51-IN-17 shows significant fungicidal activity against B. cinerea with an EC50 of 0.326 μg/mL[1].
Target Antigen
Bacterial; Cytochrome P450; Fungal
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cyp51-in-17.html
Smiles
O=C(C(C1C2=CC=CO2)=C(N)OC3=C1CN(C(C4=CC=CO4)=O)C/C3=C\C5=CC=CO5)OC
Molecular Weight
448.42
References & Citations
[1]Bao A, et al. Design, Synthesis, Bioactive Evaluation, and Molecular Dynamics Simulation of Novel 4 H-Pyrano [3, 2-c] pyridine Analogues as Potential Sterol 14α-Demethylase (CYP51) Inhibitors[J]. Journal of Medicinal Chemistry, 202
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163571/CYP51-IN-17-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163571/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
