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Lesinurad sodium

Product Specifications

CAS Number

1151516-14-1

Synonyms

Selexipag, Zurampic, RDEA-594 sodium

Target

OAT

Applications

Transmembrane Transporters

Smiles

[Na+].[O-]C (=O) CSC1=NN=C (Br) [N]1C2=CC=C (C3CC3) C4=CC=CC=C24

Molecular Formula

C17H13BrN3NaO2S

Additionnal Information

Lesinurad (Selexipag, RDEA-594) sodium (Zurampic) is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout. Lesinurad sodium inhibits the uric acid transporter URAT1 and Kidney transporter OAT with IC50/Km of 4.3 μM/0.85 μM and 3.5 μM/2 μM for OAT1 and OAT3, respectively.

Storage Conditions

3 years -20°C powder

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