Regorafenib (BAY-734506) Monohydrate
Product Specifications
CAS Number
1019206-88-2
Synonyms
Fluoro-sorafenib, Resihance, Stivarga, regorafaenib monohydrate
Target
VEGFR
Applications
Protein Tyrosine Kinase
Smiles
CNC (=O) C1=NC=CC (=C1) OC2=CC (=C (C=C2) NC (=O) NC3=CC (=C (C=C3) Cl) C (F) (F) F) F.O
Molecular Formula
C21H15ClF4N4O3.H2O
Additionnal Information
Regorafenib (BAY-734506, Fluoro-sorafenib, Resihance, Stivarga, regorafaenib monohydrate) Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, Kit (c-Kit), RET (c-RET), RAF-1, B-RAF and B-RAF (V600E) respectively.
Storage Conditions
2 years -80 in solvent
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