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Pixantrone Maleate

Product Specifications

CAS Number

144675-97-8

Synonyms

BBR-2778

Target

Topoisomerase

Applications

DNA Damage/DNA Repair

Smiles

C1=CC (=C2C (=C1NCCN) C (=O) C3=C (C2=O) C=NC=C3) NCCN.C (=CC (=O) O) C (=O) O.C (=CC (=O) O) C (=O) O

Molecular Formula

C17H19N5O2.2C4H4O4

Additionnal Information

Pixantrone (BBR-2778) is a novel aza-anthracenedione compound with antitumor activity. It is a weak topoisomerase II inhibitor and forms stable DNA adducts through alkylation with specificity for DNA hypermethylated sites.

Storage Conditions

2 years -80 in solvent

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