Irinotecan hydrochloride
Product Specifications
CAS Number
100286-90-6
Synonyms
CPT-11 hydrochloride, (+) -Irinotecan hydrochloride
Target
Topoisomerase
Applications
DNA Damage/DNA Repair
Smiles
Cl.CCC1=C2CN3C (=O) C4=C (C=C3C2=NC5=C1C=C (OC (=O) N6CCC (CC6) N7CCCCC7) C=C5) C (O) (CC) C (=O) OC4
Molecular Formula
C33H39ClN4O6
Additionnal Information
Irinotecan (CPT-11, (+) -Irinotecan) hydrochloride is an inhibitor of Topoisomerase I (Topo I) that exhibits cytotoxicity in LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively.
Storage Conditions
3 years -20°C powder
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