What is the catalog number for Ceritinib dihydrochloride?

The catalog number for Ceritinib dihydrochloride is S4967-25mg.

What sizes are available for Ceritinib dihydrochloride?

Ceritinib dihydrochloride is available in the following size(s): 25 mg.

Is Ceritinib dihydrochloride in stock?

Ceritinib dihydrochloride is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ceritinib dihydrochloride?

Ceritinib dihydrochloride is manufactured by Bimake.

What is the estimated delivery time for Ceritinib dihydrochloride?

Estimated delivery time for Ceritinib dihydrochloride is approximately 15 business day(s), depending on your location.

Ceritinib dihydrochloride

Product Specifications

CAS Number

1380575-43-8

Synonyms

Zykadia, LDK378 dihydrochloride

Target

ALK

Applications

Protein Tyrosine Kinase

Smiles

Cl.Cl.CC (C) OC1=C (NC2=NC=C (Cl) C (=N2) NC3=CC=CC=C3[S] (=O) (=O) C (C) C) C=C (C) C (=C1) C4CCNCC4

Molecular Formula

C28H38Cl3N5O3S

Additionnal Information

Ceritinib (Zykadia, LDK378) dihydrochloride is a selective, orally bioavailable and ATP-competitive inhibitor of ALK with IC50 of 0.2 nM. Ceritinib dihydrochloride also inhibits InsR, IGF-1R and STK22D with IC50 of 7 nM, 8 nM and 23 nM, respectively. Ceritinib exhibits antitomor activity.