Fostamatinib disodium hexahydrate
Product Specifications
CAS Number
914295-16-2
Synonyms
Tavalisse, R788 disodium hexahydrate, Tamatinib Fosdium hexahydrate
Target
Syk
Applications
Protein Tyrosine Kinase
Smiles
O.O.O.O.O.O.[Na+].[Na+].COC1=CC (=CC (=C1OC) OC) NC2=NC=C (F) C (=N2) NC3=NC4=C (OC (C) (C) C (=O) N4CO[P] ([O-]) ([O-]) =O) C=C3
Molecular Formula
C23H36FN6Na2O15P
Additionnal Information
Fostamatinib (R788) disodium (Tamatinib Fosdium) hexahydrate, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay.
Storage Conditions
3 years -20°C powder
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