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Cedrol

Product Specifications

CAS Number

77-53-2

Target

P450 (e.g. CYP17)

Applications

Metabolism

Smiles

CC1CCC2C13CCC (C (C3) C2 (C) C) (C) O

Molecular Formula

C15H26O

Additionnal Information

Cedrol, a natural occuring sesquiterpene alcohol, is a potent competitive inhibitor of CYP2B6-mediated bupropion hydroxylase with inhibition constant (Ki) value of 0.9 μM. It also inhibits CYP3A4-mediated midazolam hydroxylation with a Ki value of 3.4 μM while only weakly inhibits CYP2C8, CYP2C9, and CYP2C19 activities.

Storage Conditions

2 years -80 in solvent

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