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QNZ (EVP4593)

Product Specifications

CAS Number

545380-34-5

Target

NF-κB

Applications

NF-κB

Smiles

C1=CC=C (C=C1) OC2=CC=C (C=C2) CCNC3=NC=NC4=C3C=C (C=C4) N

Molecular Formula

C22H20N4O

Additionnal Information

QNZ (EVP4593) shows potent inhibitory activity toward both NF-κB activation and TNF-α production with IC50 of 11 nM and 7 nM in Jurkat T cells, respectively.

Storage Conditions

2 years -80 in solvent

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