JNK-IN-8
Product Specifications
CAS Number
1410880-22-6
Synonyms
JNK Inhibitor XVI
Target
JNK
Applications
MAPK
Smiles
CC1=C (C=CC (=C1) NC (=O) C2=CC (=CC=C2) NC (=O) C=CCN (C) C) NC3=NC=CC (=N3) C4=CN=CC=C4
Molecular Formula
C29H29N7O2
Additionnal Information
JNK-IN-8 (JNK Inhibitor XVI) is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 4.7 nM, 18.7 nM and 1 nM, >10-fold selectivity against MNK2, Fms and no inhibition to c-Kit, Met, PDGFRβin A375 cell line.
Storage Conditions
2 years -80 in solvent
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