Daminozide
Product Specifications
CAS Number
1596-84-5
Synonyms
Aminozide, DMASA, DIMG, B 995, Alar, Kylar, B-NINE, SADH
Target
Histone Demethylase
Applications
Epigenetics
Molecular Formula
C6H12N2O3
Additionnal Information
Daminozide (Aminozide, DMASA, DIMG, B 995, Alar, Kylar, B-NINE, SADH) is a plant growth regulator that selectively inhibits human KDM2/7 histone demethylases, with IC50 of 0.55 μM for PHF8 (KDM7B), 1.5 μM for KDM2A, and 2.1 μM for KIAA1718 (KDM7A) . It shows over 100-fold selectivity for the KDM2/7 subfamily compared to other histone demethylase subfamilies, with significantly weaker activity against enzymes such as KDM3A with IC50 of 127 μM.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6236445-01 0.1 mL
Cdc20 (CDC20, CDC20A, p55CDC, P55CDC-LSB) (BSA & Azide Free) (MaxLight 750)
Sign In for Pricing
View Details MBS6236445-02 5x 0.1 mL
Cdc20 (CDC20, CDC20A, p55CDC, P55CDC-LSB) (BSA & Azide Free) (MaxLight 750)
Sign In for Pricing
View Details 
MBS7011164-01 0.02 mg
Recombinant Guinea pig T-cell surface glycoprotein CD1e, membrane-associated (CD1E)
Sign In for Pricing
View Details MBS7011164-02 0.1 mg
Recombinant Guinea pig T-cell surface glycoprotein CD1e, membrane-associated (CD1E)
Sign In for Pricing
View Details MBS7011164-03 5x 0.1 mg
Recombinant Guinea pig T-cell surface glycoprotein CD1e, membrane-associated (CD1E)
Sign In for Pricing
View Details 