Lesinurad
Product Specifications
CAS Number
878672-00-5
Synonyms
RDEA 594, RDEA-594, RDEA594
Target
OAT
Applications
Transmembrane Transporters
Smiles
C1CC1C2=CC=C (C3=CC=CC=C23) N4C (=NN=C4Br) SCC (=O) O
Molecular Formula
C17H14BrN3O2S
Additionnal Information
Lesinurad (RDEA-594) is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout in combination with xanthine oxidase inhibitors. Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with Km values of 0.85 and 2 μM, respectively.
Storage Conditions
2 years -80 in solvent
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