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Nitroxoline

Product Specifications

CAS Number

4008-48-4

Synonyms

8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol, 5-Nitro-8-hydroxyquinoline

Target

Cysteine Protease

Applications

Proteases

Smiles

C1=CC2=C (C=CC (=C2N=C1) O) [N+] (=O) [O-]

Molecular Formula

C9H6N2O3

Additionnal Information

Nitroxoline (8-Hydroxy-5-nitroquinoline, 5-nitroquinolin-8-ol, 5-Nitro-8-quinolinol, 5-Nitro-8-hydroxyquinoline) is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. Nitroxoline impairs tumor progression in vitro and in vivo by inhibiting cathepsin B activity.

Storage Conditions

2 years -80 in solvent

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