What is the catalog number for PCNA-I1?

The catalog number for PCNA-I1 is S4476-25mg.

What sizes are available for PCNA-I1?

PCNA-I1 is available in the following size(s): 25 mg.

PCNA-I1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PCNA-I1?

PCNA-I1 is manufactured by Bimake.

What is the estimated delivery time for PCNA-I1?

Estimated delivery time for PCNA-I1 is approximately 15 business day(s), depending on your location.

PCNA-I1

Product Specifications

CAS Number

444930-42-1

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Smiles

CC1=C (SC=C1) C (=O) N\N=C\C2=C (O) C3=CC=CC=C3C=C2

Molecular Formula

C17H14N2O2S

Additionnal Information

PCNA-I1 is a selective inhibitor of proliferating cell nuclear antigen (PCNA, a potential anticancer target) . PCNA-I1 selectively binds to PCNA trimers with Kd of ~0.2 to 0.4 μM. PCNA-I1 inhibits the growth of tumor cells of various tissue types with IC50 of ~0.2 μM. PCNA-I1 induces DNA damage and apoptosis in both LNCaP and PC-3 cells. PCNA-I1 also induces autophagy in PC-3 cells.