IMM-H007

Product Specifications

CAS Number

1221412-23-2

Target

AMPK

Applications

PI3K/Akt/mTOR

Smiles

CC (=O) OCC1OC (C (OC (C) =O) C1OC (C) =O) [N]2C=NC3=C (NC4=CC=CC (=C4) O) N=CN=C23

Molecular Formula

C22H23N5O8

Additionnal Information

IMM-H007, an adenosine derivative, is an activator of AMP-Activated Protein Kinase (AMPK) . IMM-H007 is a potential drug for treating cardiac dysfunction. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κB and JNK/AP1 signaling. IMM-H007 inhibits ABCA1 (ATP binding cassette subfamily a member 1) degradation and facilitates its cell-surface localization in macrophages, thereby promotes cholesterol efflux.