Pimozide
Product Specifications
CAS Number
2062-78-4
Synonyms
Orap, R6238
Target
Dopamine Receptor
Applications
Neuronal Signaling
Smiles
FC1=CC=C (C=C1) C (CCCN2CCC (CC2) N3C (=O) NC4=CC=CC=C34) C5=CC=C (F) C=C5
Molecular Formula
C28H29F2N3O
Additionnal Information
Pimozide (Orap, R6238) is an antagonist of Dopamine Receptors with Ki of 0.83 nM, 3.0 nM and 6600 nM for dopamine D3, D2 and D1 receptors, respectively. Pimozide also exhibits binding affinity at 5-HT1A and α1-adrenoceptor with Ki of 310 nM and 39 nM, respectively. Pimozide is an antipsychotic drug with anti-tumor activity and suppresses STAT3 and STAT5 activity.
Storage Conditions
2 years -80 in solvent
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