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Tasimelteon

Product Specifications

CAS Number

609799-22-6

Synonyms

BMS 214778, VEC 162

Target

MT Receptor

Applications

Neuronal Signaling

Smiles

CCC (=O) NCC1CC1C2=C3CCOC3=CC=C2

Molecular Formula

C15H19NO2

Additionnal Information

Tasimelteon (BMS 214778, VEC 162) is a selective dual melatonin receptor (MT1/MT2) agonist with 2.1-4.4 times greater affinity for the MT2 receptor believed to mediate circadian rhythm phase-shifting (Ki = 0.0692 nM and Ki = 0.17 nM in NIH-3T3 and CHOeK1 cells, respectively), than for the MT1 receptor (Ki = 0.304 nM and Ki = 0.35 nM, respectively) .

Storage Conditions

3 years -20°C powder

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