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Nordihydroguaiaretic acid (NDGA)

Product Specifications

CAS Number

500-38-9

Target

Lipoxygenase

Applications

Metabolism

Smiles

CC (CC1=CC (=C (C=C1) O) O) C (C) CC2=CC (=C (C=C2) O) O

Molecular Formula

C18H22O4

Additionnal Information

Nordihydroguaiaretic acid (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub, Larrea tridentata (Sesse and Moc. ex DC) Coville (creosote bush) . It is a recognized inhibitor of lipoxygenase (LOX) and has antioxidant and free radical scavenging properties. Nordihydroguaiaretic acid (NDGA) is a cytotoxic insulin-like growth factor-I receptor (IGF-1R) /HER2 inhibitor and induces apoptosis.

Storage Conditions

2 years -80 in solvent

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