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Gentiopicroside

Product Specifications

CAS Number

20831-76-9

Synonyms

Gentiopicrin

Target

P450 (e.g. CYP17)

Applications

Metabolism

Smiles

C=CC1C (OC=C2C1=CCOC2=O) OC3C (C (C (C (O3) CO) O) O) O

Molecular Formula

C16H20O9

Additionnal Information

Gentiopicroside (GE, Gentiopicrin), a naturally occurring iridoid glycoside, inhibits CYP2A6 and CYP2E1 with IC50 values of 21.8μg/ml and 594μg/ml, respectively in human liver microsomes, and dose not inhibit CYP2C9, CYP2D6, CYP1A2 or CYP3A4 activities.

Storage Conditions

2 years -80 in solvent

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