Sodium Aescinate

Product Specifications

CAS Number

20977-05-3

Synonyms

Escin sodium salt

Target

NF-κB

Applications

NF-κB

Smiles

CC (C (C) OC (=O) C) C (=O) OCC12C3CC (C (C1O) OC2CC4 (C3=CCC5C4 (CCC6C5 (CCC (C6 (C) CO) OC7C (C (C (C (O7) C (=O) O) OC8C (C (C (C (O8) CO) O) O) O) O) OC9C (C (C (CO9) O) O) O) C) C) C) (C) C.[Na+]

Molecular Formula

C54H83NaO23

Additionnal Information

Sodium Aescinate (SA, Escin Sodium Salt) is a widely-applied triterpene saponin product derived from horse chestnut seeds, possessing vasoactive and organ-protective activities with oral or injection administration in the clinic. Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway.