NEM (N-Ethylmaleimide)
Product Specifications
CAS Number
128-53-0
Target
Cysteine Protease
Applications
Proteases
Smiles
CCN1C (=O) C=CC1=O
Molecular Formula
C6H7NO2
Additionnal Information
NEM (N-Ethylmaleimide) is an organic compound that is derived from maleic acid. It is an irreversible inhibitor of all cysteine peptidases, with alkylation occurring at the active site thiol group. N-Ethylmaleimide (NEM) inactivates endogenous deubiquitinating enzymes (DUBs) . N-Ethylmaleimide (NEM) specifically inhibits phosphate transport in mitochondria.
Storage Conditions
2 years -80 in solvent
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