Sulfaphenazole
Product Specifications
CAS Number
526-08-9
Synonyms
Depocid, Depotsulfonamide, Plisulfan, Raziosulfa
Target
P450 (e.g. CYP17)
Applications
Metabolism
Smiles
C1=CC=C (C=C1) N2C (=CC=N2) NS (=O) (=O) C3=CC=C (C=C3) N
Molecular Formula
C15H14N4O2S
Additionnal Information
Sulfaphenazole (Depocid, Depotsulfonamide, Plisulfan, Raziosulfa) is an inhibitor of CYP2C9 with Ki value of 0.3 μM and demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki values of 63 and 29 μM for CYP2C8 and CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19) .
Storage Conditions
2 years -80 in solvent
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