Berbamine dihydrochloride
Product Specifications
CAS Number
6078-17-7
Synonyms
BA, BBM
Target
Bcr-Abl
Applications
Protein Tyrosine Kinase
Smiles
CN1CCC2=CC (=C3C=C2C1CC4=CC=C (C=C4) OC5=C (C=CC (=C5) CC6C7=C (O3) C (=C (C=C7CCN6C) OC) OC) O) OC.Cl
Molecular Formula
C37H40N2O6.2HCl
Additionnal Information
Berbamine (BA, BBM) dihydrochloride, a traditional Chinese medicines extracted from Berberis amurensis (xiaoboan), is a novel inhibitor of bcr/abl fusion gene with potent anti-leukemia activity and also an inhibitor of NF-κB. Berbamine (BA, BBM) dihydrochloride induces apoptosis in human myeloma cells and inhibits the growth of cancer cells by targeting Ca2+/calmodulin-dependent protein kinase II (CaMKII) .
Storage Conditions
2 years -80 in solvent
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