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Zandelisib

Product Specifications

CAS Number

1401436-95-0

Synonyms

ME-401; PWT-143

Target

PI3K

Applications

PI3K/Akt/mTOR

Molecular Formula

C31H38F2N8O

Additionnal Information

Zandelisib (ME-401; PWT-143) is an orally bioavailable inhibitor of the phosphatidylinositide 3-kinase (PI3K) . It selectively inhibits the delta isoform of PI3K (p110δ) and prevents the activation of the PI3K/AKT signaling pathway with an IC50 of 3.5 nM. It functions as an antineoplastic agent.
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