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IDH-305

Product Specifications

CAS Number

1628805-46-8

Target

Dehydrogenase

Applications

Metabolism

Molecular Formula

C23H22F4N6O2

Additionnal Information

IDH-305 (Compound 13) is an orally available, mutant-selective and brain-penetrant inhibitor of isocitrate dehydrogenase 1 (IDH1) that targets IDH1 (R132) mutation with IC50 of 27 nM, 28 nM and 6.14 μM for IDH1R132H, IDH1R132C and IDH1WT, respectively.

Storage Conditions

3 years -20°C powder

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