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Brequinar Sodium

Product Specifications

CAS Number

96201-88-6

Synonyms

Bipenquinate, BRQ, DUP-785, NSC 368390

Target

Dehydrogenase

Applications

Metabolism

Smiles

CC1=C (C (=O) O[Na]) C2=CC (=CC=C2N=C1C3=CC=C (C=C3) C4=C (F) C=CC=C4) F

Molecular Formula

C23H14F2NNaO2

Additionnal Information

Brequinar Sodium (Bipenquinate, BRQ, DUP-785, NSC 368390) is a potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of ~20 nM and triggers differentiation in the ER-HoxA9, U937, and THP1 cells with ED50 of ~1 μM.

Storage Conditions

3 years -20°C powder

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