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VBIT-4

Product Specifications

CAS Number

2086257-77-2

Target

VDAC

Applications

Transmembrane Transporters

Smiles

OCC (CC (=O) NC1=CC=C (Cl) C=C1) N2CCN (CC2) C3=CC=C (OC (F) (F) F) C=C3

Molecular Formula

C21H23ClF3N3O3

Additionnal Information

VBIT-4 is a voltage-dependent anion channel (VDAC) oligomerization inhibitor that decreases mitochondrial DNA (mtDNA) release, type I interferon (IFN) signaling, neutrophil extracellular traps, and disease severity in a mouse model of systemic lupus erythematosus.

Storage Conditions

3 years -20°C powder

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