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HSP27 inhibitor J2

Product Specifications

CAS Number

2133499-85-9

Synonyms

J2

Target

HSP (HSP90)

Applications

Cytoskeletal Signaling

Molecular Formula

C13H12O4S

Additionnal Information

HSP27 inhibitor J2 (J2) is an inhibitor of HSP27, which induces abnormal HSP27 dimers formation and suppresses the generation of HSP27 giant polymers, inhibiting the chaperone role of HSP27 and diminishing its cellular protective function. HSP27 inhibitor J2 (J2) enhances the antiproliferative activity of 17-AAG and increases the sensitivity of cisplatin-induced lung cancer cell growth inhibition.

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