Demethyleneberberine
Product Specifications
CAS Number
25459-91-0
Synonyms
DMB
Target
Peroxidases
Applications
Metabolism
Smiles
COC1=C (OC) C2=C[N+]3=C (C=C2C=C1) C4=CC (=C (O) C=C4CC3) O
Molecular Formula
C19H18NO4
Additionnal Information
Demethyleneberberine (DMB), a component of Cortex Phellodendri Chinensis (CPC), significantly alleviates the weight loss and diminishes myeloperoxidase (MPO) activity, while significantly reduces the production of pro-inflammatory cytokines, such as interleukin (IL) -6 and tumor necrosis factor-α (TNF-α), and inhibits the activation of NF-κB signaling pathway. Demethyleneberberine (DMB) potentially ameliorates NAFLD (Non-alcoholic fatty liver disease) by activating AMPK pathways.
Storage Conditions
3 years -20°C powder
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