Tyrosinase-IN-22
Tyrosinase-IN-22 (compound 4) is an inhibitor of tyrosinase substrates (L-tyrosine and L-dopa) with IC50s of 60 nM and 30 nM, respectively. Tyrosinase-IN-22 also shows potent antioxidant and anti-melanogenic properties, thus can be used for relevant researches[1].
Product Specifications
CAS Number
[25369-78-2]
Product Name Alternative
5-Chloro-2-mercaptobenzimidazole
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Reactive Oxygen Species (ROS) ; Tyrosinase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tyrosinase-in-22.html
Purity
99.75
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
S=C1NC2=CC(Cl)=CC=C2N1
Molecular Formula
C7H5ClN2S
Molecular Weight
184.65
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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