Senkyunolide I
Product Specifications
CAS Number
94596-28-8
Synonyms
SEI, SENI
Target
ERK
Applications
MAPK
Smiles
CCC\C=C1/OC (=O) C2=C1CCC (O) C2O
Molecular Formula
C12H16O4
Additionnal Information
Senkyunolide I (SEI, SENI) is an orally active compound isolated from Ligusticum chuanxiong with analgesic, anti-migraine, neuroprotective, anti-oxidation and anti-apoptosis activities. Senkyunolide I (SEI, SENI) up-regulates the phosphorylation of Erk1/2 and induces Nrf2 nuclear translocation with enhanced HO-1 and NQO1 expressions. Senkyunolide I (SEI, SENI) promotes the ratio of Bcl-2/Bax and inhibits the expressions of cleaved caspase 3 and caspase 9.
Storage Conditions
3 years -20°C powder
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