UCB-9260
Product Specifications
CAS Number
1515888-53-5
Target
TNF-alpha
Applications
Apoptosis
Smiles
C[N]1C=C (C=N1) C2=CC3=C (C=C2) N=C (C (O) C4=CC=NC=C4) [N]3CC5=C (C) C=CC (=C5) C
Molecular Formula
C26H25N5O
Additionnal Information
UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13 nM. UCB-9260 also inhibits NF-κB with IC50 of 202 nM after TNF stimulation.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
