SBI-477
Product Specifications
CAS Number
781628-99-7
Target
IGF-1R
Applications
Protein Tyrosine Kinase
Molecular Formula
C24H25N3O6S
Additionnal Information
SBI-477 is an insulin signaling inhibitor that deactivates the transcription factor MondoA, leading to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4) . SBI-477 inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes.
Storage Conditions
3 years -20°C powder
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